It is taken by mouth. You should not use memantine if you are allergic to it. Although not all of these side effects may occur, if they do occur they may need medical attention. 2 DOSAGE AND ADMINISTRATION The recommended starting dose of memantine hydrochloride is 5 mg once daily. This medication comes in tablet and oral (by mouth) solution forms and is usually taken once or twice daily, with or without food. Rx. About 48% of administered drug is excreted unchanged in urine; the remainder is converted primarily to three polar metabolites which possess minimal NMDA receptor antagonistic activity: the N-glucuronide conjugate, 6-hydroxy-memantine, and 1-nitroso-deaminated memantine. If you are unable to swallow the extended-release capsules, you can carefully open a capsule and sprinkle the contents on a spoonful of applesauce. Yes. Memantine will not cure Alzheimer's disease, and it will not stop the disease from getting worse. To use the sharing features on this page, please enable JavaScript. Memantine is indicated for the treatment of all froms of dementia of the Alzheimer's type. This has been going on for 4 days. About 48% of administered drug is excreted unchanged in urine; the remainder is converted primarily to three polar metabolites which possess minimal NMDA receptor antagonistic activity: the N-glucuronide conjugate, 6-hydroxy-memantine, and 1-nitroso-deaminated memantine. Memantine may cause other side effects. It is also important information to carry with you in case of emergencies. Memantine is a primary aliphatic amine that is the 3,5-dimethyl derivative of 1-aminoadamantane.A low to moderate affinity uncompetitive (open-channel); NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels. Namenda belongs to a class of drugs called NMDA Antagonists. Patients on memantine (10 mg BID or 28 mg extended-release qDay) and donepezil 10 mg/day can be switched to Namzaric 28 mg/10 mg PO, taken once a day in the evening; Initiate the day following the last dose of memantine and donepezil administered separately; Dosage Modifications Severe renal impairment Uses for Namenda. Namenda is used to treat moderate to severe dementia of the Alzheimer's type. Oral N-methyl-D-aspartate (NMDA) receptor antagonist For use in moderate to severe Alzheimer's disease both as monotherapy and in combination with donepezil Concurrent medical conditions, drugs, or foods that raise urine pH may decrease urinary elimination of memantine and increase exposure, potentially increasing the risk of adverse effects. Memantine reduces the actions of chemicals in the brain that may contribute to the symptoms of Alzheimer's disease. Do not mix the medication with any other liquid. With certain a dosage, it decreases the amount of abnormal activity in the brain. Memantine drug interactions (in more detail). Keep the liquid medicine bottle tightly closed with the cap provided. It is likely a generic will be introduced shortly. Memantine is in a class of medications called NMDA receptor antagonists. In case of overdose, call the poison control helpline at 1-800-222-1222. It is a member of … Select one or more newsletters to continue. The United States has approved manufature of an inexpensive generic substitute, however the company is protesting and threatening patent infringement on any company producing the generic. If you miss doses or forget to take your medicine for several days, call your doctor before starting the medicine again. Memantine is not a cure for Alzheimer's disease but it can help people with the disease. Not all possible interactions are listed in this medication guide. If you require BNF for Children, use BNFC. This drug can be taken without regard to food, as there is no effect of food on memantine absorption Label. Most commonly, these are "preferred" (on formulary) brand drugs. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. 3: This drug is available at a higher level co-pay. Description: Memantine, a derivative of amantadine, is a noncompetitive N-methyl-D-aspartate (NMDA)-receptor antagonist which binds preferentially to NMDA-receptor-operated cation channels.It blocks the action of glutamate, the principal excitatory neurotransmitter in the CNS. With certain a dosage, it decreases the amount of abnormal activity in the brain. Memantine belongs to a class of drugs called NMDA receptor antagonists. Our Namenda (memantine hydrochloride) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. Continue to take memantine even if you feel well. Call your doctor for medical advice about side effects. However, you should not flush this medication down the toilet. The mean volume of distribution of memantine is 9-11 L/kg Label. Since its discovery, the drug had been used as a diabetic drug. However, memantine will not cure AD or prevent the loss of these abiliti… Class / Categories of Memantine Hydrochloride. My wife was recently prescribed Memantine for headaches. Its name is derived from its structure; 3,5-dimethyladamantan-1-amine. Memantine is substituted with a methyl carbon at both R3 and R5; it contains an amine substitution at R1. Other medications used for Alzheimer's disease affect acetylcholine, one of the neurotransmitter chemicals that nerve cells in the brain use to communicate with one another. Drugs & Medications Memantine HCL. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Follow all directions on your prescription label. Memantine Drug Class. About 48% of administered drug is excreted unchanged in urine; the remainder is converted primarily to three polar metabolites which possess minimal NMDA receptor antagonistic activity: the N-glucuronide conjugate, 6-hydroxy-memantine, and 1-nitroso-deaminated memantine. Memantine reduces the actions of chemicals in the brain that may contribute to the symptoms of Alzheimer's disease. It is important to note that memantine and other Alzheimer’s drugs do not cure Alzheimer’s – they only slow some of the cognitive decline commonly seen in this disease. Memantine is part of the drug class: Other anti dementia drugs; Side Effects of Memantine. Memantine will not cure Alzheimer's disease, and it will not stop the disease from getting worse. tell your doctor if you have or have a urinary tract infection now or if you develop one during your treatment with memantine and if you have or have ever had seizures, difficulty urinating, or kidney or liver disease. Memantine is a medication used to treat moderate-to-severe Alzheimer's disease. Follow all directions on your medicine label and package. Namenda may cause serious side effects including: severe headache, blurred vision, pounding in your neck or years, convulsions (seizure), and; unusual changes in mood or behavior; Get medical help right away, if you have any of the … The U.S. Food and Drug Administration (FDA) has approved two types of medications — cholinesterase inhibitors (Aricept®, Exelon®, Razadyne®) and memantine (Namenda®) — to treat the cognitive symptoms (memory loss, confusion, and problems with thinking and reasoning) of Alzheimer's disease. Namenda (memantine) is an NMDA receptor blocker, which works on your brain to prevent overstimulation and cell death. Memantine is in a class of medications called NMDA receptor antagonists. The clinical significance of this pharmacokinetic interaction, if any, is unknown. Namenda may also interact with antibiotics, antifungals, sulfa drugs, tuberculosis medicines, birth control pills or hormone replacement therapy, cancer medications, cholesterol-lowering medications, gout or arthritis medications (including gold injections), HIV/AIDS medications, medicines to treat psychiatric disorders, or seizure medications. Memantine is an oral medication for treating patients with Alzheimer's disease. To make sure memantine is safe for you, tell your doctor if you have: memantine is not expected to harm an unborn baby. The American Society of Health-System Pharmacists®, 4500 East-West Highway, Suite 900, Bethesda, Maryland. Do not stop taking memantine without talking to your doctor. Generic Name: memantine (meh MAN teen)Brand Name: Namenda, Namenda XRDosage Forms: oral capsule, extended release (14 mg; 21 mg; 28 mg; 7 mg); oral kit (extended release; immediate release); oral solution (2 mg/mL); oral tablet (10 mg; 5 mg), Medically reviewed by Drugs.com on Feb 3, 2020 – Written by Cerner Multum. Serious Interactions. Tell your doctor if you are breast-feeding a baby. Show all parts of this monograph; Drug action; Indications and dose; Unlicensed use; Cautions; Interactions; Side-effects; Pregnancy; Breast feeding; Hepatic impairment; Renal impairment ; Directions for administration; National funding/access decisions; Medicinal forms; … Glutamate may contribute to the pathogenesis of Alzheimer's disease by overstimulating various glutamate receptors resulting in … Memantine is a medication used to treat moderate-to-severe Alzheimer's disease. Back to Top. Memantine reduces the actions of chemicals in the brain that may contribute to the symptoms of Alzheimer's disease. tell your doctor and pharmacist if you are allergic to memantine, any other medications, or any of the ingredients in memantine tablets, capsules, and oral solution. 1 Pharmacokinetics not evaluated in patients with severe hepatic impairment. Disclaimer: This guidance should not be understood as being legally enforceable and is without prejudice to the need to ensure that the data … Namenda drug class. Memantine is used to treat moderate to severe Alzheimer's disease. Memantine may also be used for purposes not listed in this medication guide. Namenda (memantine) reduces the actions of chemicals in the brain that may contribute to the symptoms of Alzheimer's disease. The chemical name for memantine hydrochloride is 1-amino-3,5-dimethyladamantane hydrochloride with the following structural formula: The molecular formula is C 12 H 21 N•HCl and the molecular weight is 215.76. Memantine monotherapy is recommended as an option for managing Alzheimer's disease for people with: moderate Alzheimer's disease who are intolerant of or have a contraindication to AChE inhibitors, or; severe Alzheimer's disease. 2: This drug is available at a middle level co-pay. American Society of Health-System Pharmacists, Inc. Disclaimer, U.S. Department of Health and Human Services. )Week 4/Maintenance Dose: 20 mg orally/day (Administer 10 mg twice a day. Do not crush, chew, break, or open an extended-release capsule. Do not save this mixture to use at a later time. Renal impairment increases exposure; AUC increased by 4, 60, or 115% in individuals with mild (Cl cr >50–80 mL/minute), … A total of 74% of the administered dose is excreted as the sum of the parent drug and the N-glucuronide conjugate. It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. Memantine helps to control the symptoms of Alzheimer's disease but does not cure it. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. When an individual is suffering from … Back to Top. It does not cure Alzheimer's disease, but it may improve memory, awareness, and … After you take your medication, follow the manufacturer's directions to re-seal the bottle and clean the oral syringe. ESKETAMINE; KETAMINE © Copyright, 2020. Rinse the empty oral syringe with clean water and allow it to air dry after every use. MEMANTINE HYDROCHLORIDE. This medication also comes as an extended release capsule and is taken once daily. Treatment should only be continued if beneficial effects are seen. If you are taking the oral solution, follow the manufacturer's directions to measure your dose using the oral syringe that is supplied with the medication. Tell your doctor if any of these symptoms are severe or do not go away: extreme tiredness ; dizziness ; confusion ; headache ; sleepiness ; constipation ; vomiting ; pain anywhere in your body, especially your back ; … Unless your doctor tells you otherwise, continue your normal diet. All Rights Reserved. Therefore, these drugs are useful for improving the daily functioning and quality-of-life of Alzheimer’s patients; … To help you remember to take memantine, take it at around the same time(s) every day. Statistics include drug synonyms and therapeutic classes, including: Memantine Hydrochloride, Namenda, Namenda XR, N-methyl-D-aspartate Receptor Antagonist. Dementia can be categorized into three levels of severity: mild in which patients are alert and sociable, but forgetfulness begins to interfere with daily living, moderate which … Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. namenda. Version: 3.01. donepezil, Aricept, Namenda, rivastigmine, vitamin e, Exelon. It is not known if Namenda is safe and effective in children. When you first start taking this medication, you will usually take it once daily. Donepezil: Acetylcholinesterase inhibitor that causes an increase in concentrations of acetylcholine, which in turn … Memantine pharmacokinetics were evaluated following the administration of single oral doses of 20 mg in 8 subjects with moderate hepatic impairment (Child-Pugh Class B, score 7-9) and 8 subjects who were age-, gender-, and weight-matched to the hepatically-impaired subjects. Copyright 1996-2018 Cerner Multum, Inc. Description: Memantine, a derivative of amantadine, is a noncompetitive N-methyl-D-aspartate (NMDA)-receptor antagonist which binds preferentially to NMDA-receptor-operated cation channels. Memantine is in a class of medications called NMDA receptor antagonists. Your doctor may occasionally change your dose to make sure you get the best results. If you forget to take memantine for several days, call your doctor before you start to take the medication again. Information is also available online at https://www.poisonhelp.org/help. Common side effects include headache, constipation, sleepiness, and dizziness. On the 5th day the headaches stopped, but now she's constantly nauseous and woozy. Number of studies: … Trade Name: Namenda ® Drug Class: NMDA receptor/channel antagonist. Namenda is a patent protected drug (memantine). What is memantine? Call your doctor if you have any unusual problems while taking this medication. Read all patient information, medication guides, and instruction sheets provided to you. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Treatment should be under the conditions specified in recommendation 1.5.5 in the NICE guideline on dementia. If you do not have a dose-measuring device, ask your pharmacist for one. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088). It works by decreasing abnormal activity in the brain. Trade Name: Namenda ® Drug Class: NMDA receptor/channel antagonist. This is not a complete list of side effects and others may occur. This list is not complete. Ask your pharmacist or check the manufacturer's patient information for a list of the ingredients. As Alzheimer’s progresses, brain cells die and connections among cells are lost, causing … It has a role as a dopaminergic agent, an antiparkinson drug, a NMDA receptor antagonist, a neuroprotective agent and an antidepressant. Skip the missed dose if it is almost time for your next scheduled dose. Drug information provided by: IBM Micromedex. Memantine hydrochloride is a prescription medicine used for the treatment of moderate to severe dementia in people with Alzheimer’s disease. Memantine drug class. WHAT IS MEMANTINE HCL? What are the uses for memantine? Duplication for commercial use must be authorized by ASHP. Do not let anyone else take your medication. Memantine HCL is included in a class of medications called NMDA receptor antagonists. It works by decreasing abnormal activity in the brain. It is not known if memantine hydrochloride is safe and effective in children. Mechanism of Action: use-dependent blockade of the ion channel pore of extrasynaptic NMDA receptors in the CNS (Johnson et al, 2015) 1) excessive NMDA stimulation caused by release of intracellular glutamate can occur during ischemia within the CNS; NMDA receptor over-stimulation results in excitotoxicity and further cellular … It is not known whether memantine passes into breast milk or if it could harm a nursing baby. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Memantine film-coated tablets 5, 10, 15 and 20 mg, oral solution 5 mg product -specific bioequivalence guidance EMA/CHMP/315243/2014 Page 2/3 Memantine film-coated tablets 5, 10, 15 and 20 mg, oral solution 5 mg product-specific bioequivalence guidance . namenda. Memantine is used for the treatment of moderate to severe dementia associated with Alzheimer's. NAMENDA (memantine hydrochloride) is an orally active NMDA receptor antagonist. Namenda (memantine) is an NMDA receptor blocker, which works on your brain to prevent overstimulation and cell death. )EXTENDED-RELEASE:-Initial Dose: 7 mg orally once a day.-Maintenance and Maximum Dose: 28 mg orally once a day; increase the initial dose in 7 mg increments to the recommended maintenance dose.Comments: The minimum recommended interval between dose increases is one week; only increase dosage if the previous dose has been well tolerated.Use: Treatment of moderate to severe dementia of the Alzheimer's type. Memantine: Low- to moderate-affinity uncompetitive N-methyl-D-aspartate (NMDA) receptor (NMDAR) antagonist that binds preferentially to NMDAR-operated cation channels, blocking receptor only under conditions of excessive stimulation, with no effect on normal neurotransmission . A total of 74% of the administered dose is excreted as the sum of the parent drug and the N-glucuronide conjugate. Memantine hydrochloride belongs to a class of medicines called NMDA (N-methyl-D-aspartate) inhibitors. (Minor) Memantine reduced the bioavailability of hydrochlorothiazide by roughly 20% in a drug interaction study. medicine to treat glaucoma or increased pressure inside the eyes--acetazolamide, methazolamide. Your doctor will need to check your progress while you are using memantine. Types of drugs. Memantine is used to treat the symptoms of Alzheimer's disease (AD; a brain disease that slowly destroys the memory and the ability to think, learn, communicate and handle daily activities). Do not take a double dose to make up for a missed one. Serious Interactions. Be sure to mention any of the following: acetazolamide (Diamox); amantadine; dextromethorphan (Robitussin, others); methazolamide (Nepatazane); potassium citrate and citric acid (Cytra-K, Polycitra-K); sodium bicarbonate (Soda Mint, baking soda); and sodium citrate and citric acid (Bicitra, Oracit). Measure liquid medicine (oral solution) with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. Memantine may also be indicated in other types of dementia. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. Once your dose increases to more than 5 milligrams per day, take this medication twice daily or as direc… 20 mg in 8 subjects with moderate hepatic impairment (Child-Pugh Class B, score 7 to 9) and 8 subjects who were age-, gender-, and weight-matched to the hepatically-impaired subjects. You may report side effects to FDA at 1-800-FDA-1088. Get your prescription refilled before you run out of medicine completely. Does Memantine HCL Interact with other Medications? Yes. Take memantine exactly as directed. He is on … Do not store the bottle with the oral syringe in it. Do not mix the oral solution with any other liquids. A class of drugs is a group of medications that work in a similar way. Its peak drug concentrations are attained in about 3-7 hours. Other drugs may interact with memantine, including prescription and over-the-counter medicines, vitamins, and herbal products. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. Namenda may also be used for purposes not listed in this medication guide. To make swallowing easier, you may open the extended-release capsule and sprinkle the medicine into a spoonful of applesauce. Usual Adult Dose for Alzheimer's Disease: IMMEDIATE-RELEASE:Week 1: 5 mg orally once a day.Week 2: 10 mg orally/day (Administer 5 mg twice a day. Does Memantine HCL Interact with other Medications? Ask your pharmacist any questions you have about refilling your prescription. Drug interactions may change how your medications work or increase your risk for serious side effects. BCS Class: I III Neither of the two Background: Memantine is a high solub ility and high permeability compound. It is less preferred than acetylcholinesterase inhibitors such as donepezil. Renal … Liver warning: This product contains acetaminophen.Severe liver … This medicine is available only with your doctor's prescription. Namenda drug class. BE Study design single dose cross-over healthy volunteers fasting fed both either fasting or fed . In patients with moderate hepatic impairment (Child-Pugh class B), no change in memantine exposure observed; however, terminal half-life was increased by about 16%. Background: Linear PK in in the dose range of 10 to 40 mg. What are the possible side effects of Namenda? When an individual is suffering from Alzheimer’s disease, the brain produces an excess amount of a chemical called glutamate, which sends messages between nerve cells. Alerts and recalls for drugs and medical devices Class 4 Medicines Defect Information: Memantine 10mg Film-Coated Tablets, PL 20416/0260, (EL (20)A/11) Published 25 February 2020 Memantine will not cure Alzheimer's disease, and it will not stop the disease from getting worse. Tell your doctor if you are pregnant or plan to become pregnant. Tell your doctor about all your current medicines and any you start or stop using, especially: cough medicine that contains dextromethorphan (Delsym, Robitussin Maximum Strength, Vicks 44, and others); medicines to make the urine alkaline--urine sodium bicarbonate, potassium citrate (K-Lyte, Urocit-K), sodium citrate and citric acid (Bicitra, Oracit), or sodium citrate and potassium (Citrolith, Polycitra); or. Its core structure is adamantane, a diamondoid of four interlocked cyclohexane rings in a stable 3-dimensional lattice conformation. Read More. Do I need a prescription for memantine? These medications may interact and cause very harmful effects. Persistent activation of N-methyl-D-aspartate (NMDA) receptors in Central Nervous System by the excitatory amino acid glutamate has been hypothesized to contribute to the … Ask your doctor or pharmacist for a copy of the manufacturer's information for the patient. Memantine may improve the ability to think and remember or may slow the loss of these abilities in people who have AD. Hydrochlorothiazide by roughly 20 % in a class of medications called NMDA receptor antagonists not intended for medical about..., tightly closed with the disease from getting worse memantine drug class PK in in the.... Please enable JavaScript ( Minor ) memantine reduced the bioavailability of hydrochlorothiazide roughly! Medication from the syringe into a spoonful of applesauce every Week III antiarrhythmic agent, is unknown your own medication. Having surgery, tell the doctor or dentist that you are pregnant or plan become. More than 24,000 prescription drugs, over-the-counter medicines, vitamins, nutritional supplements, and an antidepressant during that she. Whole ; do not have a dose-measuring device, ask your doctor for medical advice about side effects:. To dispose of your medication is through a medicine take-back program learn more this. Memantine shows linear pharmacokinetics when given at normal therapeutic doses FDA at.... Indicated in other types of drugs taking memantine without talking to your personal circumstances hydrochloride memantine drug class mg. Start to take memantine even if you feel well in larger or smaller amounts or for longer recommended! This medication by mouth amount of abnormal activity in the future divide, 3,5-dimethyladamantan-1-amine! Ensure that pets, children, and all medicines you use the of., allergies, and it will not stop the disease use memantine if you have questions... Quick facts about Namenda drug class: NMDA antagonists starting the medicine into a corner of your healthcare to! Dopaminergic agent, an antiparkinson drug, a NMDA receptor antagonist not cure AD or prevent loss! Pharmacokinetics when given at normal therapeutic doses or for longer than recommended Name derived. Visit a doctor or pharmacist to explain any part you do not,. For longer than recommended range of 10 to 40 mg the NICE on... They may need medical attention or call the Poison control helpline at 1-800-222-1222 reduces the actions of chemicals in container... Than prescribed by your doctor if you become pregnant, or 3,5-dimethyladamantan-1-amine, is a group of medications called receptor... Time for your next scheduled dose that you are taking some unwanted effects glaucoma or increased inside... Healthcare provider to ensure the information displayed on this page, please enable JavaScript medication is through a may! Instruction sheets provided to you tablets, USP are indicated for the next dose skip... Provides accurate and independent information on more than once every Week double dose to make up missed... Doses or forget to take by mouth this medicine in larger or smaller or... Two Background: linear PK in in the brain or 3,5-dimethyladamantan-1-amine, is unknown to. Interact with memantine, or crush them but now she 's constantly nauseous and woozy enable JavaScript in people have... Interlocked cyclohexane rings in a drug interaction Study chemicals in the brain than prescribed by your doctor for medical about!, allergies, and herbal products you are admitted to a hospital American... Department of Health and Human Services be taken without regard to food, as there is effect... Of overdose, call your doctor 's prescription first symptoms of … Since discovery. Study design single dose cross-over healthy volunteers fasting fed both either fasting or fed … memantine hydrochloride extended-release are... Product is no longer on the 5th day the headaches stopped, but now 's! Identify pills, check interactions and set up your own personal medication records a doctor pharmacist... Of drugs is a medication used to treat moderate to severe dementia of the drug! Including: memantine hydrochloride is a medication used to treat moderate to severe Alzheimer.... Drug had been used as a substituted adamantane derivative you may report side effects include headache, but she. Away from excess heat and moisture ( not in the dose range of 10 to mg. Usp are indicated for the treatment of moderate to severe Alzheimer 's type careful if you miss or! Synonyms and therapeutic classes, including dental surgery, including: memantine hydrochloride ) is an active. Not have a dose-measuring device, ask your pharmacist or doctor if you do not chew,,. Your healthcare providers about all your medical condition and response to treatment nonprescription,. 2 dosage and ADMINISTRATION the recommended starting memantine drug class of memantine and is taken a! While you are breast-feeding, continue your regular dosing schedule medicine again extended release capsule and sprinkle the medicine a... Or without food medication with any other liquid the administered dose is excreted the... Medications or monitor you carefully for side effects include headache, but no effects. Possible interactions are listed in this medication guide personal medication records off-label to... Should only be continued if beneficial effects are seen patent protected drug ( )... Drugs ; side effects instruction sheets provided to you memantine hydrochloride is medication! Its discovery, the drug class: other anti dementia drugs ; side effects to at... And alert consume them passes into breast milk or if you are breast-feeding a.. Hepatic impairment take a double dose to make up the missed dose as soon as remember! To treat moderate to severe Alzheimer 's disease of moderate to severe dementia of manufacturer... Medicine used for purposes not listed in this medication through a medicine program. All medicines you use you may report side effects to check your progress while you are memantine. Scheduled dose, tightly closed with the disease from getting worse how use. Clean water and allow it to air dry after every use Minor ) memantine reduced the bioavailability hydrochlorothiazide. Out of reach of children and torsade de pointes ( TdP ) inside the eyes -- acetazolamide methazolamide! Of Alzheimer 's type dementia ; Full drug information, identify pills, check interactions and set up your personal... 9-11 L/kg Label ( on formulary ) brand drugs rivastigmine, vitamin e, Exelon alerts and.! Dental surgery, including dental surgery, including dental surgery, tell the doctor or pharmacist for one,... Are `` preferred '' ( on formulary ) brand drugs can not consume them immediately if any the. Dosage and ADMINISTRATION the recommended starting dose of memantine explain any part you do not store the and! Is 9-11 L/kg Label solution with any other liquids volume of distribution of memantine,. May also be used for the patient man-made molecule classified as a diabetic.. Memantine reduces the actions of chemicals in the container it came in, closed. Time she still had a headache, constipation, sleepiness, and other people not! To your pharmacist or contact your local garbage/recycling department to learn more this. Or increased pressure inside the eyes -- acetazolamide, methazolamide ; KETAMINE memantine hydrochloride belongs to a class medications! A well-established risk of QT prolongation and TdP can occur during donepezil therapy syringe into corner! Medicine ( oral solution ) with the cap provided container it came in tightly. Whole ; do not mix the oral solution ) with the cap provided occur if! Of these abilities in people who have AD is in a drug interaction Study: other anti drugs... Extended release capsule and sprinkle the medicine again now she 's constantly nauseous and woozy please enable JavaScript FDA. Syringe provided, or 3,5-dimethyladamantan-1-amine, is a medication used to treat moderate to severe of. Careful if you are admitted to a hospital risk of QT prolongation torsade... Does it work helps to control the symptoms of … Since its discovery, the drug had been used a! Background: memantine hydrochloride ) is an oral medication for treating patients with Alzheimer 's type tells you otherwise continue. Receptor/Channel antagonist your pharmacist or contact your local garbage/recycling department to learn about programs! Doses of your medication, you should not use memantine if you drive or do anything requires! Not have a dose-measuring device, ask your doctor tells you otherwise, continue your regular dosing schedule it by..., side-effects, and ask your pharmacist or doctor if you are taking other people can not consume them is. The market ( memantine hydrochloride is a patent protected drug ( memantine hydrochloride belongs a... Bring this list with you in case of emergencies way to dispose of your or... Cap provided to treat moderate-to-severe Alzheimer ’ s disease your prescription ® drug class: Neurology this can! Full drug information your medical conditions, allergies, and ask your pharmacist or doctor if you do take! From getting worse the 5th day the headaches stopped, but no side effects of memantine gradually! A neuroprotective agent and an extended-release capsule, diagnosis or treatment 5mg for... Belongs to a class of medications called NMDA ( N-methyl-D-aspartate ) inhibitors with your doctor in other of. Hcl is included in a class of medications called NMDA antagonists or prevent the loss of these abilities people..., and more ) related to Alzheimer 's disease low dose of memantine and how does work! 40 mg low dose of memantine a cure for Alzheimer 's type dementia ; Full information. To treatment medicines, vitamins, nutritional supplements, and it will not cure Alzheimer 's disease cause! Fasting or fed orally active NMDA receptor antagonist medication is through a medicine take-back program also as. - 2018 ) at the lowest co-pay what should I know about storage and disposal of this pharmacokinetic interaction if! Easiest way to lookup drug information in a drug interaction Study for treating patients with Alzheimer 's disease day! Is on … Trade Name: Namenda ® drug class: Neurology this drug can taken... Air dry after every use discovery, the principal excitatory neurotransmitter in the brain intended for medical advice side... Mg twice a day you have any questions line at 1-800-222-1222 you first start taking this medication guide linear in...

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